@article {Almeida2016,
	title = {A biocompatible hybrid material with simultaneous calcium and strontium release capability for bone tissue repair},
	journal = {Materials Science and Engineering: C},
	volume = {62},
	year = {2016},
	month = {03/2016},
	pages = {429-438},
	chapter = {429},
	abstract = {<p>The increasing interest in the effect of strontium in bone tissue repair has promoted the development of bioactive materials with strontium release capability. According to literature, hybrid materials based on the system PDMS{\textendash}{}SiO2 have been considered a plausible alternative as they present a mechanical behavior similar to the one of the human bone. The main purpose of this study was to obtain a biocompatible hybrid material with simultaneous calcium and strontium release capability. A hybrid material, in the system PDMS{\textendash}{}SiO2{\textendash}{}CaO{\textendash}{}SrO, was prepared with the incorporation of 0.05 mol of titanium per mol of SiO2. Calcium and strontium were added using the respective acetates as sources, following a sol{\textendash}{}gel technique previously developed by the present authors. The obtained samples were characterized by FT-IR, solid-state NMR, and SAXS, and surface roughness was analyzed by 3D optical profilometry. In vitro studies were performed by immersion of the samples in Kokubo{\textquoteright}s SBF for different periods of time, in order to determine the bioactive potential of these hybrids. Surfaces of the immersed samples were observed by SEM, EDS and PIXE, showing the formation of calcium phosphate precipitates. Supernatants were analyzed by ICP, revealing the capability of the material to simultaneously fix phosphorus ions and to release calcium and strontium, in a concentration range within the values reported as suitable for the induction of the bone tissue repair. The material demonstrated to be cytocompatible when tested with MG63 osteoblastic cells, exhibiting an inductive effect on cell proliferation and alkaline phosphatase activity.</p>
},
	keywords = {Biocompatible, Hybrid materials, peer-reviewed, Strontium},
	issn = {09284931},
	doi = {10.1016/j.msec.2016.01.083},
	author = {Almeida, J. Carlos and Andr{\'a}s Wacha and Gomes, Pedro S. and Alves, Lu{\'\i}s C. and Fernandes, M. Helena Vaz and Salvado, Isabel M. Miranda and Fernandes, M. Helena R.}
}
@book {101,
	title = {X-ray Data Booklet},
	year = {2009},
	month = {2009 October},
	publisher = {Lawrence Berkeley National Laboratory, University of California},
	organization = {Lawrence Berkeley National Laboratory, University of California},
	address = {Berkeley, CA},
	url = {http://xdb.lbl.gov},
	author = {Attwood, David and Gullikson, Eric and Howells, Malcolm and Kim, Kwang-Je and Kirz, Janos and Kortright, Jeffrey and Lindau, Ingolf and Liu, Yanwei and Pianetta, Piero and Robinson, Arthur and Scofield, James and Underwood, James and Williams, Gwyn and Winick, Herman}
}
@article {106,
	title = {Structural Description of the Nickel Part of a Raney-Type Catalyst by Using Anomalous Small-Angle X-ray Scattering},
	journal = {Journal of Physical Chemistry CJournal of Physical Chemistry C},
	volume = {112},
	year = {2008},
	month = {2008-03-27},
	pages = {4427-4429},
	isbn = {1932-7447},
	url = {http://pubs.acs.org/cgi-bin/doilookup/?10.1021/jp800237b},
	author = {B{\'o}ta, Attila and Varga, Zolt{\'a}n and Goerigk, G{\"u}nter}
}
@article {105,
	title = {Unbinding Transition in Lipid Multibilayers Induced by Copper(II) Ions},
	journal = {The Journal of Physical Chemistry BThe Journal of Physical Chemistry B},
	volume = {112},
	year = {2008},
	month = {07/2008},
	pages = {8430-8433},
	isbn = {1520-6106, 1520-5207},
	url = {http://pubs.acs.org/doi/abs/10.1021/jp802451j},
	author = {Varga, Zolt{\'a}n and B{\'o}ta, Attila and Goerigk, G{\"u}nter}
}
@book {100,
	title = {Small angle X-ray scattering},
	year = {1982},
	month = {1982},
	pages = {540},
	publisher = {Academic Press},
	organization = {Academic Press},
	address = {New York},
	keywords = {Science / Physics / Electromagnetism, Science / Radiation, Small-angle scattering, Small-angle x-ray scattering, Small-angle x-ray scattering - Scientific applications, Small-angle x-ray scattering/ Scientific applications, Technology \& Engineering / General, X-ray crystallography, X-ray crystallography - Scientific applications, X-ray crystallography/ Scientific applications, X-rays},
	isbn = {9780122862809},
	url = {http://physchem.kfunigraz.ac.at/sm/Software.htm},
	author = {Glatter, Otto and Kratky, Otto}
}
@book {98,
	title = {Small-angle scattering of X-rays},
	year = {1955},
	month = {1955},
	publisher = {John Wiley \& Sons, Inc.},
	organization = {John Wiley \& Sons, Inc.},
	edition = {1},
	address = {New York},
	url = {http://books.google.hu/books?id=5zRRAAAAMAAJ},
	author = {Guinier, Andr{\'e} and Fournet, G{\'e}rard}
}
